HEYL

Chemisch-pharmazeutische Fabrik GmbH & Co. KG

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Home » Pharma

Pharma

11.05.2016

Wilson JP et al. 2015; Decorporation of systemically distributed americium by a novel orally administered diethylenetriaminepentaacetic Acid (DTPA) formulation in beagle dogs; Health Phys. 108(3):308-18

Study design: Beagle dogs received various doses of NanoDTPATM capsules to decorporate administered 241Americium (241Am). Efficacy of NanoDTPATM was compared to intravenously … » More

Posted in Antidota
11.05.2016

Shankar GN et al. 2014; Evaluating the toxicity of novel Zn-DTPA tablet formulation in dogs and rats; Drug Dev. Res. 75(1):37-46

Study design: Beagle dogs were treated with increasing doses of trisodium zinc pentetate (Zn-DTPA) in a novel oral solid tablet form for seven days to determine its toxicity … » More

Posted in Antidota
11.05.2016

Schwartz JB et al. 2016; Response of vitamin D concentration to vitamin D3 administration in older adults without sun exposure: A randomized double-blind trial; J. Am. Geriatr. Soc. 64(1):65-72

Study design: Randomized double-blind investigation to evaluate the 25 OHD levels in elderly nursing home residents after 16 weeks when 800, 2 000 or 4 000 IU/day or 50 000 … » More

Posted in Vitamin D3
11.05.2016

Välimäki VV et al. 2016; How well are the optimal serum 25OHD concentrations reached in high-dose intermittent vitamin D therapy? A placebo-controlled study on comparison between 100 000 IU and 200 000 IU of oral D3 every 3 months in elderly women; Clin. Endocrinol. 84(6):837-44

Study design: Elderly women received 100 000 or 200 000 IU of vitamin D3 or placebo orally every 3 months plus 1 g of calcium daily over one year to test intermittent … » More

Posted in Vitamin D3
11.05.2016

Almeida MR et al. 2015; Effects of maternal vitamin B6 deficiency and over-supplementation on DNA damage and oxidative stress in rat dams and their offspring; Food Chem. Toxicol. 80:201-5

Study design: Female rats were fed with standard diet, 30 mg/kg vitamin B6 supplemented diet or deficient diet during mating, pregnancy and lactation. The offspring was … » More

Posted in Vitamin B6
11.05.2016

Shobeiri F et al. 2015; Clinical effectiveness of vitamin E and vitamin B6 for improving pain severity in cyclic mastalgia; Iran. J. Nurs. Midwifery Res. 20(6):723-7

Study design: Female patients suffering from cyclic mastalgia received 200 IU vitamin E or 40 mg vitamin B6 daily for 2 months, randomised in a double-blinded clinical trial, … » More

Posted in Vitamin B6
11.05.2016

Seishima R et al. 2016; Sulfasalazine, a therapeutic agent for ulcerative colitis, inhibits the growth of CD44v9+ cancer stem cells in ulcerative colitis-related cancer; Clin. Res. Hepatol. Gastroenterol. 40(4):487-93

Study design: This retrospective study compared the expression of cancer stem cell surface marker CD44v9+ and proliferation of CD44+ cancer cells in patients treated with … » More

Posted in Pharma
11.05.2016

Baset MA et al. 2015; Effectiveness of methotrexate and sulfasalazine alone versus methotrexate and sulphasalazine combination in the treatment of rheumatoid arthritis; Bangladesh J. Med. 26(2):67-75

Study design: In this comparative descriptive study 30 patients suffering from rheumatoid arthritis (RA) received either methotrexate (MTX), sulfasalazine (SSZ) or MTX plus … » More

Posted in Rheuma
11.05.2016

Montejo C et al. 2004; Time delay avoids interaction between guar gum and sulphadiazine after oral administration; J. Drug Deliv. Sci. Technol. 14(5):395-9

Study design: In a two-way-cross-over design volunteers received sulphadiazine alone or one hour after an oral dose of guar gum. Drug and metabolite levels were measured up … » More

Posted in Toxoplasmose
11.05.2016

Köksal ZS et al. 2016; In vivo efficacy of drugs acting on Toxoplasma gondii combined with immunomodulators; Jpn. J. Infect. Dis. 69(2):113-7

Study design: Treatment of T. gondii infected mice with various combinations of sulphadiazine and pyrimethmamine plus levamisole or echinacea to determine their influence on … » More

Posted in Toxoplasmose

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latest abstract

11.05.2016

Wilson JP et al. 2015; Decorporation of systemically distributed americium by a novel orally administered diethylenetriaminepentaacetic Acid (DTPA) formulation in beagle dogs; Health Phys. 108(3):308-18

Study design: Beagle dogs received various doses of NanoDTPATM capsules to decorporate administered 241Americium (241Am). Efficacy of NanoDTPATM was compared to intravenously … » More

Company portrait

Company portrait

Subsidiaries

Subsidiaries

Pharma

Poisoning

Anyone could become a victim to a poisoning, be it intentional or unintentinal. With their range of antidotes, the company HEYL offers many medically important counteragents to poisonings with heavy metals and radionuclides.

Rheumatoid Arthritis

Rheumatoid arthritis is the most common inflammatory joint disease, with 0.5 to 1% of the world's population suffering from it. The company HEYL has been offering rheumatic therapeutics since its establishment, facilitating the lives of those affected.

Specific Vitamin Deficiency

Vitamins are essential for many vital functions of the human body. Our organism often cannot, or only insufficently, synthesize these organic bonds by itself. That is why vitamins need to be taken up with our diet.

Toxoplasmosis

Although this infectious disease, caused by microscopically small parasites, is mostly asymptomatic, it must be treated with an antibiotic during pregnancy or in the case of immunocompromised patients to prevent serious consequences.

Morbus Wilson

Humans that are affected by this hereditary metabolic disorder can no longer secrete ingested copper. In untreated cases this results in severe damage to the brain and liver. An antidote developed specifically against copper may be the best method here.

Chemistry

Reagents

Special reagents for analysis are combined in the group Gnoste [Gnosis (γνῶσις), ancient Greek for knowledge)

APIs

From an active pharmaceutical ingredient (API) to a finished pharmaceutical


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    Supply notes

    On stock again:
    Dimaval (DMPS) 100 mg Hartkapseln pack size 10 hard capsules

    Metalcaptase 300 mg pack size 100 tablets – Please note our information letter on the now available batches (LOTs 30000895, 30000897,30000896 and 30000898) with regard to delayed release of the active substance, which can be found at Online-Nachricht: Information der Hersteller: Informationsschreiben zu Metalcaptase® (Penicillamin) 300 mg: Inverkehrbringen von Chargen mit verzögerter Wirkstofffreisetzung | ABDA


    Currently out of stock:

    Metalcaptase 150 mg until 2026

    Metalcaptase 300 mg pack size 50 tablets. The 100 tablet pack size can be used.

    We regret the current unavailability of the products.