HEYL

Chemisch-pharmazeutische Fabrik GmbH & Co. KG

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Home » Pharma (: Page 2)

Pharma

11.05.2016

Mendoza FA et al. 2016; Severe eosinophilic fasciitis: Comparison of treatment with D-penicillamine plus corticosteroids versus corticosteroids alone; Scand. J. Rheumatol. 45(2):129-34

Study design: Long term prospective non-randomised trial to compare therapeutic effectiveness of corticosteroids (CS) and CS plus D-penicillamine (D-pen) in patients with … » More

Posted in Pharma
11.05.2016

Brancaleone V et al. 2016; D-penicillamine modulates hydrogen sulfide (H2S) pathway through selective inhibition of cystathionine-gamma-lyase (CSE); Br. J. Pharmacol. 173(9):1556-65

Study design: D-penicillamine (D-pen) was tested on mouse artoa rings for its vasodilatory effect as a possible cysteine analogue and its effect on H2S … » More

Posted in Pharma
11.05.2016

Karakulak UN et al. 2015; An arrhythmic episode after mercury exposure and successful treatment with chelation therapy: A case report; Anatol. J. Cardiol. 15:586-91

Study design: This report surveys the case of a female patient presenting weakness of the limbs, malaise, fatigue, atypical chest pain and palpitation due to mercury … » More

Posted in Antidota
11.05.2016

Gaidukov SN et al. 2013; Features of the early neonatal period at children born from mothers with the critical values of mercury in their blood; Mod. Problems Sci. Educat. No. 6

Study design: This study compared several neonatal parameters of babies born by mothers with critical level of mercury in their blood who were either treated (group 1) with … » More

Posted in Antidota
04.05.2016

Mirzoev EB et al. 2015; The influence of hexacyanoferrate (II) potassium-ferric(III) as a radionuclide sorbent fed at different doses on clinical, hematological and physiological parameters in rats; Agric. Biol. 50(2):237-44

Study Design: Wistar rats received 0 mg/kg, 11.6 mg/kg, 23.2 mg/kg or 32.4 mg/kg  hexacyanoferrate (II) potassium-ferric (III) orally for 30 days to compare influence on … » More

Posted in Antidota
29.04.2016

Parajuli D et al. 2013; Prussian blue nanoparticles for the enrichment of radioactive cesium in colutions; Waste Management Conference: International collaboration and continuous improvement, Phoenix, AZ (USA), 24-28 Feb 2013

Study Design: Prussian Blue (PB) nanoparticles in various forms were compared for their ability to adsorb cesium (Cs) from water. Results: Water dispersible nano-PB could … » More

Posted in Antidota
18.02.2015

Langlois DK et al. 2013; Pharmacokinetics and relative bioavailability of D-penicillamine in fasted and nonfasted dogs; J. Vet. Intern. Med. 27(5): 1071-6

Study Design: Dogs received D-penicillamine (12.5 mg/kg PO) fasted and with food in a randomized, crossover design to test the effect if food on the … » More

Posted in Antidota, Morbus Wilson

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latest abstract

02.06.2025

Strategic Stockpiling in CBRN Emergencies

Strategic Stockpiling in CBRN Emergencies has become a vital part of modern crisis preparedness. In a world shaped by unpredictable threats, especially in the context of … » More

Company portrait

Company portrait

Subsidiaries

Subsidiaries

Pharma

Poisoning

Anyone could become a victim to a poisoning, be it intentional or unintentinal. With their range of antidotes, the company HEYL offers many medically important counteragents to poisonings with heavy metals and radionuclides.

Rheumatoid Arthritis

Rheumatoid arthritis is the most common inflammatory joint disease, with 0.5 to 1% of the world's population suffering from it. The company HEYL has been offering rheumatic therapeutics since its establishment, facilitating the lives of those affected.

Specific Vitamin Deficiency

Vitamins are essential for many vital functions of the human body. Our organism often cannot, or only insufficently, synthesize these organic bonds by itself. That is why vitamins need to be taken up with our diet.

Toxoplasmosis

Although this infectious disease, caused by microscopically small parasites, is mostly asymptomatic, it must be treated with an antibiotic during pregnancy or in the case of immunocompromised patients to prevent serious consequences.

Morbus Wilson

Humans that are affected by this hereditary metabolic disorder can no longer secrete ingested copper. In untreated cases this results in severe damage to the brain and liver. An antidote developed specifically against copper may be the best method here.

Chemistry

Reagents

Special reagents for analysis are combined in the group Gnoste [Gnosis (γνῶσις), ancient Greek for knowledge)

APIs

From an active pharmaceutical ingredient (API) to a finished pharmaceutical


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    Supply notes

    Metalcaptase 300 mg pack size 100 tablets – Please note our information letter on the batches 30000895, 30000897,30000896 and 30000898 with regard to delayed release of the active substance, which can be found at Online-Nachricht: Information der Hersteller: Informationsschreiben zu Metalcaptase® (Penicillamin) 300 mg: Inverkehrbringen von Chargen mit verzögerter Wirkstofffreisetzung | ABDA


    Currently out of stock:

    Metalcaptase 150 mg until presumably 2026

    Metalcaptase 300 mg until presumably Q4/2025

    We regret the current unavailability of the products.

    Talk to your doctor whether one of the following penicillamine-containing medicines could be used as an alternative: KELATINE 300 mg comprimidos revestidos (from Portugal), CUPRENIL, 250 mg, tabletki powlekane (from Poland) or Cupripen 250 mg cápsulas duras (from Spain).